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Computational Biology


Biologia computazionale

L’attività di ricerca ha come obiettivo lo sviluppo di algoritmi efficienti e scalabili per l’analisi di dati biologici e genomici per derivare conoscenza di alta qualità e in tempi brevi in vari a


Alessio Vecchio

Foto di Alessio Vecchio

Filippo Geraci

Foto di Filippo Geraci

Marco Pellegrini

Foto di Marco Pellegrini

Maria Elena Renda

Foto di Maria Elena Renda

Mauro Leoncini

Foto di Mauro Leoncini


EU Network of Excellence - VPH Virtual Physiological Human Network of Excellence

The VPH NoE is a project which aims to help support and progress European research in biomedical modelling and simulation of the human body.

Pubblicazioni e prodotti editoriali prima del 01/01/2016

Ab initio detection of fuzzy amino acid tandem repeats in protein sequences

A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs

An Efficient Combinatorial Approach for Solving the DNA Motif Finding Problem

Characterization and identification of hidden rare variants in the human genome

Circulating microRNAs in metastatic colorectal cancer (mCRC) patients (pts) treated with regorafenib

CNVScan: detecting border- line copy number variations in NGS data via scan statistics

Comprehensive reconstruction and visualization of non-coding regulatory networks in human

Computational Design of Artificial RNA Molecules For Gene Regulation

Detecting Fuzzy Amino Acid Tandem Repeats in Protein Sequences

Detection of Genomic Structural Variants from Next-Generation Sequencing Data

Exploiting whole-exome sequencing data to identify copy number variants

FPF-SB: a Scalable Algorithm for Microarray Gene Expression Data Clustering

Information Technology in Bio- and Medical Informatics, Proceedings of the 3rd International Conference ITBAM 2012

Information Technology in Bio- and Medical Informatics, Proceedings of the 4th International Conference ITBAM 2013

Information Technology in Bio- and Medical Informatics, Proceedings of the 5th International Conference ITBAM 2014

Information Technology in Bio- and Medical Informatics, Proceedings of the 6th International Conference ITBAM 2015

K-Boost: A Scalable Algorithm for High-Quality Clustering of Microarray Gene Expression Data

Methods for the Identification of PTEN-Targeting MicroRNAs

miMETA: an online meta-analysis tool for the miRandola database

miR-26a targets identification in prostate cancer cell lines using miRNA pull-out assay

miR-28-5p showed a tumor suppressive activity in DU-145 prostate cancer cells and regulated E2F6

miRandola: towards a comprehensive resource for non-invasive biomarkers

OCDB: the first overall database collecting genes, miRNAs and drugs for Obsessive-Compulsive Disorder

Proceedings of the VIII Annual Meeting of the Bioinformatics Italian Society

Ranking of candidate microRNA-target pairs sensitive to disease and cell-line conditions

Tandem Repeats Discovery Service (TReaDS) applied to finding novel Cis-acting factors in Repeat Expansion Diseases

TReaDS: Tandem Repeats Discovery Service

TRStalker: an Efficient Heuristic for Finding Fuzzy Tandem Repeats

TRStalker: an Efficient Heuristic for Finding NP-Complete Tandem Repeats

Use of prostate cancer cells as in vitro model for discovering miRNAs released by cells that developed docetaxel resistance

Pubblicazioni e prodotti editoriali dal 01/01/2016

Analysis of DNA tandem repeats in ALS from Whole Genome Sequencing: Role of FRA10Ac1 gene repeat expansion in ALS

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

Disease associated tandem repeat genotyping from NGS target sequencing data

Identification of Disease–miRNA Networks Across Different Cancer Types Using SWIM

Information Technology in Bio- and Medical Informatics, Proceedings of the 7th International Conference ITBAM 2016

Information Technology in Bio- and Medical Informatics, Proceedings of the 8th International Conference ITBAM 2017

miR-182-5p is an evolutionarily conserved Tbx5 effector that impacts cardiac development and electrical activity in zebrafish

Systematic analysis of the involvement of DNA tandem repeats in Amyotrophic lateral sclerosisfrom Whole Genome Sequencing data

The miR-28-5p Targetome Discovery Identified SREBF2 as One of the Mediators of the miR-28-5p Tumor Suppressor Activity in Prostate Cancer Cells

Using XCAVATOR and EXCAVATOR2 to Identify CNVs from WGS, WES, and TS Data

Offerte di lavoro

Call for Expression of Interest for a Doctoral fellowship in Bioinformatics