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Computational Biology

Activities

Computational Biology

The objective of the research is the development of efficient and scalable algorithms for high throughput analysis of biological and genomic data, in order to help getting useful indication in a -h

People

Filippo Geraci

Foto di Filippo Geraci

Manuela Montangero

Foto di Manuela Montangero

Marco Pellegrini

Foto di Marco Pellegrini

Maria Elena Renda

Foto di Maria Elena Renda

Mauro Leoncini

Foto di Mauro Leoncini

Projects

EU Network of Excellence - VPH Virtual Physiological Human Network of Excellence

The VPH NoE is a project which aims to help support and progress European research in biomedical modelling and simulation of the human body.

Publications and editorial products until 01/01/2016

Ab initio detection of fuzzy amino acid tandem repeats in protein sequences

A knowledge base for the discovery of function, diagnostic potential and drug effects on cellular and extracellular miRNAs

An Efficient Combinatorial Approach for Solving the DNA Motif Finding Problem

Characterization and identification of hidden rare variants in the human genome

Circulating microRNAs in metastatic colorectal cancer (mCRC) patients (pts) treated with regorafenib

CNVScan: detecting border- line copy number variations in NGS data via scan statistics

Comprehensive reconstruction and visualization of non-coding regulatory networks in human

Computational Design of Artificial RNA Molecules For Gene Regulation

Detecting Fuzzy Amino Acid Tandem Repeats in Protein Sequences

Detection of Genomic Structural Variants from Next-Generation Sequencing Data

Exploiting whole-exome sequencing data to identify copy number variants

FPF-SB: a Scalable Algorithm for Microarray Gene Expression Data Clustering

Information Technology in Bio- and Medical Informatics, Proceedings of the 3rd International Conference ITBAM 2012

Information Technology in Bio- and Medical Informatics, Proceedings of the 4th International Conference ITBAM 2013

Information Technology in Bio- and Medical Informatics, Proceedings of the 5th International Conference ITBAM 2014

Information Technology in Bio- and Medical Informatics, Proceedings of the 6th International Conference ITBAM 2015

K-Boost: A Scalable Algorithm for High-Quality Clustering of Microarray Gene Expression Data

Methods for the Identification of PTEN-Targeting MicroRNAs

miMETA: an online meta-analysis tool for the miRandola database

miR-26a targets identification in prostate cancer cell lines using miRNA pull-out assay

miR-28-5p showed a tumor suppressive activity in DU-145 prostate cancer cells and regulated E2F6

miRandola: towards a comprehensive resource for non-invasive biomarkers

OCDB: the first overall database collecting genes, miRNAs and drugs for Obsessive-Compulsive Disorder

Proceedings of the VIII Annual Meeting of the Bioinformatics Italian Society

Ranking of candidate microRNA-target pairs sensitive to disease and cell-line conditions

Tandem Repeats Discovery Service (TReaDS) applied to finding novel Cis-acting factors in Repeat Expansion Diseases

TReaDS: Tandem Repeats Discovery Service

TRStalker: an Efficient Heuristic for Finding Fuzzy Tandem Repeats

TRStalker: an Efficient Heuristic for Finding NP-Complete Tandem Repeats

Use of prostate cancer cells as in vitro model for discovering miRNAs released by cells that developed docetaxel resistance

Publications and editorial products from the 01/01/2016

Context-dependent miR-204 and miR-211 affect the biological properties of amelanotic and melanotic melanoma cells

Information Technology in Bio- and Medical Informatics, Proceedings of the 7th International Conference ITBAM 2016

Databases

ERCIM Postdoctoral Researcher